Components of Smallpox Vaccine	Excipients Table Allergens Table Components Table
Indication Active immunity against vaccinia and smallpox Proprietary Name Dryvax Manufacturer Wyeth Viability Live attenuated Microorganism Double-stranded DNA vaccinia virus genus orthopoxvirus Dose 2 to 3 pressures or punctures Route Percutaneous using bifurcated needle Dose form Powder for suspension Appearance Glossy and cloudy suspension Concentration   Full-strength 108 pock-forming units/mL Administered dose 2.5 x 105 pock-forming units Preservatives Phenol 0.25% Adjuvant None Excipients Brilliant green diluent until the 1980’s. Since 2002 diluent no longer brilliant green Allergens Calf lymph, Polymyxin B, 100 units/mL Dihydrostreptomycin, 200 mcg/mL Chlortetracyclin, 200 mcg/mL Neomycin, 100 mcg/mL Media Skin of vaccinated bovine calves Packaging Vial and Diluent for 100 vaccinations Routine Storage 2 to 8° C Shipped at 0° C or cooler updated July 2005
This page was last updated on August 02, 2010 © 2005 Institute for Vaccine Safety