Components of

Japanese Encephalitis Vaccines

Components Page
Excipients Table
Allergens Table
       
Name Ixiaro JE-VAX
Manufacturer Valneva Sanofi Pasteur
Viability Inactivated Inactivated
Indicated Ages 2 months and older 1 year and older
Dose 0.5 mL 1.0 mL
Schedule 2 doses: 28 days apart 3 doses: 0, 7, 30 days; abbreviated schedule 0 , 7, 14 days)
Route Subcutaneous Subcutaneous
Appearance White, opaque, non-uniform suspension which becomes homogeneous upon shaking A colorless, transparent liquid
Concentration Purified inactivated JEV, 6 mcg
Preservative None Thimerosal, 0.007%
Adjuvant None None
Excipients • Formaldehyde, <200 ppm
• Bovine serum albumin, <100 ng/mL
• Host cell DNA, < 200 pg/mL
• Sodium Metabisulphit, < 100 ng/mL
• Host cell Protein, <100 ng/mL
• Protamine Sulfate, <1 mcg/mL
• Gelatin, 500 mcg
• Formaldehyde, <100 mcg
• Polysorbate 80, <0.0007% v/v
• Mouse serum protein, <50 ng
Allergens • Mouse-serum protein, <50 ng - no myelin basic protein can be detected at the detection threshold of the assay (< 2 ng/mL)
• Gelatin, 500 mcg
• Thimerosal, 0.007%
Media Vero Cells
Packaging Single dose pre-filled syringe with plunger stopper, with or without a seperate needle • Single dose vial + diluent
• 10-dose vial + diluent
Storage 2-8C (36-46F)
Do not freeze
2-8C (35-46F)
Do not freeze
PI date April 2018 December 2005
    table last updated 4/25/18