Components of

Hepatitis A+B Vaccine

Components Page
Excipients Table
Allergens Table
Name Twinrix  
Manufacturer GlaxoSmithKline Biologicals
Indicated Ages 18 years and older  
Dose 1 mL  
Schedule Standard: 3 doses
Accelerated: 4 doses + booster
Route Intramuscular in deltoid region
Appearance Uniform hazy white  
Concentration • Hepatitis A, 720 ELISA units
• HBsAg protein, 20 mcg
Preservative None  
Adjuvant Aluminum phosphate and aluminum hydroxide, 0.45 mg/mL
Excipients Formalin, ≤0.1 mcg
MRC-5 cellular proteins, ≤2.5 mcg
Neomycin sulfate, ≤20 ng
Yeast protein, ≤5%
Unspecified amounts:
Amino acids
Sodium chloride
Phosphate buffer
Polysorbate 20
Allergens The tip caps of the prefilled syringes contain natural rubber latex
Media MRC-5 human diploid cells
Saccharomyces cerevisiae yeast cells
Packaging Vials, single and 10-packs
Prefilled syringes, single and 10-packs
Storage 2 to 8 C (35-46 F) - Do Not Freeze
PI date December 2016  
  table last updated 3/12/18