Components of

Human Papillomavirus Vaccines

Components Page
Excipients Table
Allergens Table
     
Name Gardasil Gardasil 9
Manufacturer Merck Merck
Viability Inactivated Inactivated
Indicated Ages 9-26 years 9-26 years
Dose 0.5 mL 0.5 mL
Schedule 3 doses Ages 9-14 years: 2 doses (3 doses if dose #2 is given less than 5 months after dose #1)
Ages 15-26 years: 3 doses
Route Intramuscular Intramuscular
Appearance White and cloudy White and cloudy
Concentration HPV 6 L1 protein, 20 mcg
HPV 11 L1 protein, 40 mcg
HPV 16 L1 protein, 40 mcg
HPV 18 L1 protein, 20 mcg
HPV type 6 L1 protein, 30 mcg
HPV type 11 L1 protein, 40 mcg
HPV type 16 L1 protein, 60 mcg
HPV type 18 L1 protein, 40 mcg
HPV type 31 L1 protein, 20 mcg
HPV type 33 L1 protein, 20 mcg
HPV type 45 L1 protein, 20 mcg
HPV type 52 L1 protein, 20 mcg
HPV type 58 L1 protein, 20 mcg
Preservative None None
Adjuvant Amorphous aluminum hydroxyphosphate sulfate, 225 mcg aluminum Amorphous Aluminum Hydroxyphosphate Sulfate (AAHS)
Excipients Polysorbate 80, 50 mcg
L-histindine, 0.78 mg
Sodium Borate, 35 mcg
Sodium Chloride, 9.56 mg
Yeast, <7 mcg
Aluminum, 500 mcg
Sodium Chloride, 9.56 mg
L-histidien, 0.78 mg
Polysorbate 80, 50 mcg
Sodium borate, 35 mcg
Yeast protein, <7 mcg
Allergens "The VLPs are released from the yeast cells by cell disruption and purified by a series of chemical and physical methods." "The VLPs are released from the yeast cells by cell disruption and purified by a series of chemical and physical methods."
Media "chemically-defined fermentation media which include vitamins, amino acids, mineral salts, and carbohydrates." "chemically-defined fermentation media which include vitamins, amino acids, mineral salts, and carbohydrates."
Packaging Single-dose (0.5 mL) vials
Disposable prefilled syringes
10-pack single dose vials
10-pack prefilled syringes
Storage 2-8C (36-46F)
Do not freeze. Protect from light.
2-8C (35-46F)
Do not freeze
PI date Apr 2015 Feb 2018
    Table last updated 7/18/18